Scientist, Mouse Genetics and Outsourced breeding management (m/f/d)

Beschreibung

As a first-tier supplier to our renowned business partner F. Hoffmann-La Roche Ltd. in Basel, we are currently looking for a motivated and dedicated Scientist, Mouse Genetics and Outsourced breeding management for a temporary assignment of 12 months.

Tasks & Responsibilities

• Provide high-level oversight of external Contract Research Organizations (CROs) and internal breeding facilities to ensure operational excellence.
• Develop and implement optimized breeding strategies (with focus on quality, timelines and costs) to maintain genetic stability while minimizing surplus animals, aligning with the 3Rs (Replacement, Reduction, Refinement).
• Serve as the primary point of contact for external vivarium managers, troubleshooting issues related to phenotype drift, or health status etc.
• Act as internal expert for the generation of new mouse lines using cutting-edge techniques.
• Define and standardize the official nomenclature for all newly generated lines in accordance with MGI (Mouse Genome Informatics) and International Committee guidelines.
• Maintain meticulous records of genotypes and molecular validation data (e.g., NGS, Southern Blot, qPCR).
• Monitor the health and welfare of experimental cohorts, defining ?humane endpoints? and overseeing the assessment of unexpected phenotypes in new transgenic lines.
• Develop and implement standards in housing and care of contract bred animals at external partners.
• Collaborate with therapeutic area experts to provide initial phenotypic characterization and validation of model utility.

Must-Haves

• PhD in Genetics, Molecular Biology, Biotechnology, or a related field
• Minimum 3+ years of hands-on experience in mouse genetics and colony management
• Proven track record of generating mouse models
• Strong project management skills; ability to manage multiple external vendor Relationships
• Regulatory: Familiarity with FELASA guidelines and animal welfare legislation
• Fluent written and verbal communications skills in English, German nice to have

Benefits

• Work with modern and up-to-date tools in an innovative work environment
• Experience a work culture that promotes diversity and inclusion and where all employees feel valued
• Benefit from financial support for your professional development plans
• Take advantage of unbeatable, year-round discounts at renowned retailers and over 200 top brands
• Benefit from fleet discounts when purchasing new cars or receive constant fuel discounts with our fuel card
• Become part of one of the most prestigious pharmaceutical companies and actively shape the future of healthcare
• Work on a state-of-the-art campus featuring green spaces, meeting areas, and an inspiring atmosphere
• Take advantage of attractive fitness and swimming pool facilities or the gaming room as a creative retreat
• Enjoy a selection of high-quality meals in modern staff restaurants
• As part of a sustainable mobility concept, on-site parking spaces are available to you, provided you meet the relevant qualifications
• Start with a professional onboarding process and a thorough introduction to your new role during the Welcome Days

Are you interested? Don't hesitate and submit your complete application documents online today. We look forward to hearing from you!